Chapter 14. Proteomic Studies of Human Lymphocytes: New Insights into HIV Lymphocyte Infection?

  1. Dr. Jean-Charles Sanchez,
  2. Dr. Garry L. Corthals,
  3. Prof. Dr. Denis F. Hochstrasser
  1. Dr. Françoise Vuadens1,
  2. David Crettaz1,
  3. Amalio Telenti2,
  4. Dr. Manfredo Quadroni3,
  5. Michel A. Duchosal4,
  6. Prof. Dr. Philippe Schneider1,
  7. Prof. Dr. Jean-Daniel Tissot1

Published Online: 20 SEP 2004

DOI: 10.1002/3527601562.ch14

Biomedical Applications of Proteomics

Biomedical Applications of Proteomics

How to Cite

Vuadens, F., Crettaz, D., Telenti, A., Quadroni, M., Duchosal, M. A., Schneider, P. and Tissot, J.-D. (2004) Proteomic Studies of Human Lymphocytes: New Insights into HIV Lymphocyte Infection?, in Biomedical Applications of Proteomics (eds J.-C. Sanchez, G. L. Corthals and D. F. Hochstrasser), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601562.ch14

Editor Information

  1. Biomedical Proteomics Research Group, Laboratoire Central de Chimie Clinique, Hopitaux Universitaires de Genève, 24, rue Micheli-du-Crest, 1211 Genève 14, Switzerland

Author Information

  1. 1

    Fondation Centre de Transfusion Sanguine Croix-Rouge Suisse, Lausanne, 27, rue du Bugnon, 1005 Lausanne, Switzerland

  2. 2

    Institut de Microbiologie de l'Université de Lausanne, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland

  3. 3

    Institut de Biochimie, Faculté de Médecine de l'Université de Lausanne, 1066 Epalinges, Switzerland

  4. 4

    Service d'Hématologie, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland

Publication History

  1. Published Online: 20 SEP 2004
  2. Published Print: 27 JAN 2004

ISBN Information

Print ISBN: 9783527308071

Online ISBN: 9783527601561

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Keywords:

  • lymphocytes;
  • human immunodeficiency virus;
  • applications in HIV physiopathology

Summary

  • Introduction

    • The Lymphocytes

    • Human Immunodeficiency Virus and the Lymphocytes

  • Proteomics of Lymphocytes

    • Isolation of Lymphocytes

    • Two-dimensional Electrophoresis and Mass Spectrometry

  • Results and Discussion

    • (Preliminary) Reference Lymphocyte Map (IPG: 3–10 NL)

    • Differential Expression of Proteins in CD4, CD8, and CD 19 Lymphocytes

    • Applications in HIV Physiopathology

  • Summary

  • References