Chapter 8. Clinical Proteomics: Ovarian Cancer

  1. Dr. Jean-Charles Sanchez,
  2. Dr. Garry L. Corthals,
  3. Prof. Dr. Denis F. Hochstrasser
  1. Prof. Dr. Ayodele A. Alaiya

Published Online: 20 SEP 2004

DOI: 10.1002/3527601562.ch8

Book Title

Biomedical Applications of Proteomics

Biomedical Applications of Proteomics

Additional Information

How to Cite

Alaiya, A. A. (2004) Clinical Proteomics: Ovarian Cancer, in Biomedical Applications of Proteomics (eds J.-C. Sanchez, G. L. Corthals and D. F. Hochstrasser), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601562.ch8

Editor Information

  1. Biomedical Proteomics Research Group, Laboratoire Central de Chimie Clinique, Hopitaux Universitaires de Genève, 24, rue Micheli-du-Crest, 1211 Genève 14, Switzerland

Author Information

  1. Unit of Cancer Proteomics, Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Hospital, 17176 Stockholm, Sweden

Publication History

  1. Published Online: 20 SEP 2004
  2. Published Print: 27 JAN 2004

ISBN Information

Print ISBN: 9783527308071

Online ISBN: 9783527601561

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Keywords:

  • ovarian cancer;
  • clinical proteomics;
  • protein profiling technologies;
  • RNA expression analysis;
  • tumor complexity;
  • disease prognosis

Summary

  • Introduction

  • General Background

    • Ovarian Cancer

    • Ovarian Tumor Markers

    • Screening Methods and Diagnostic Difficulties in Ovarian Tumors

    • Treatment and Prognosis of Ovarian Tumors

  • Cancer Proteomics

    • Protein Profiling and Cancer

    • RNA Expression Analysis in Cancer Cells: Promises and Pitfalls

    • Potentials and Limitations of Current Protein Profiling Technologies

    • Unravelling Tumor Complexity Prior to Proteome Analysis

    • The Future of Clinical Proteomics: Challenges and Opportunities

  • Short Overview of Ovarian Cancer Proteomics

    • The Promise of Proteomics in Ovarian Cancer Diagnostics

    • Analysis of Tissue Samples

    • Analysis of Serum Samples

    • Disease Prognosis and Protein Expression Data

  • Acknowledgements

  • References

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