Chapter 3. Structure and Function of Signal Pathways

  1. Prof. Dr. Gerhard Krauss

Published Online: 11 MAY 2004

DOI: 10.1002/3527601864.ch3

Biochemistry of Signal Transduction and Regulation, Third Edition

Biochemistry of Signal Transduction and Regulation, Third Edition

How to Cite

Krauss, G. (2004) Structure and Function of Signal Pathways, in Biochemistry of Signal Transduction and Regulation, Third Edition, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527601864.ch3

Author Information

  1. Laboratorium für Biochemie, Universität Bayreuth, 95440 Bayreuth, Germany

Publication History

  1. Published Online: 11 MAY 2004
  2. Published Print: 7 AUG 2003

ISBN Information

Print ISBN: 9783527305919

Online ISBN: 9783527601868

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Keywords:

  • signal pathways;
  • intercellular communication;
  • signal transduction;
  • extracellular signaling;
  • hormone receptors;
  • signal amplification

Summary

This chapter contains sections titled:

  • General Function of Signal Pathways

  • Structure of Signaling Pathways

    • The Mechanisms of Intercellular Communication

    • Principles of Intracellular Signal Transduction

    • Components of Intracellular Signal Transduction

    • Coupling of Proteins in Signaling Chains

  • Extracellular Signaling Molecules

    • The Chemical Nature of Hormones

    • Hormone Analogs: Agonists and Antagonists

    • Endocrine, Paracrine and Autocrine Signaling

    • Direct Modification of Protein by Signaling Molecules

  • Hormone Receptors

    • Recognition of Hormones by Receptors

    • The Interaction between Hormone and Receptor

  • Signal Amplification

  • Regulation of Inter- and Intracellular Signaling

  • Membrane Anchoring and Signal Transduction

    • Myristoylation

    • Palmitoylation

    • Farnesylation and Geranylation

    • The Glycosyl-Phosphatidyl-Inositol Anchor (GPI Anchor)

    • The Switch Function of Lipid Anchors