Chapter 6. Biocatalytic Approaches for the Large-Scale Production of Asymmetric Synthons

  1. Dr. Hans-Ulrich Blaser2,
  2. Dr. Elke Schmidt3
  1. Nicholas M. Shaw,
  2. Karen T. Robins,
  3. Andreas Kiener

Published Online: 13 JAN 2004

DOI: 10.1002/3527602151.ch6

Book Title

Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions

Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions

Additional Information

How to Cite

Shaw, N. M., Robins, K. T. and Kiener, A. (2004) Biocatalytic Approaches for the Large-Scale Production of Asymmetric Synthons, in Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions (eds H.-U. Blaser and E. Schmidt), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602151.ch6

Editor Information

  1. 2

    Solvias AG, P.O. Box, CH-4002 Basel, Switzerland

  2. 3

    Syngenta Crop Protection AG, CH-4058 Basel, Switzerland

Author Information

  1. Lonza AG, Department of Biotechnology, CH-3930 Visp, Switzerland

Publication History

  1. Published Online: 13 JAN 2004
  2. Published Print: 6 NOV 2003

ISBN Information

Print ISBN: 9783527306312

Online ISBN: 9783527602155

SEARCH

CHAPTER TOOLS

Get PDF (115K)

Keywords:

  • biocatalytisis;
  • asymmetric synthons;
  • racemic mixtures

Summary

This chapter contains sections titled:

  • Introduction

  • Asymmetric Biocatalysis

    • L-Carnitine

    • Asymmetric Reduction: (S)-Ethyl-4,4,4-trifluorohydroxybutanoate

  • Resolution of Racemic Mixtures

    • (R)- and (S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid

    • (S)-2,2-Dimethylcyclopropane Carboxamide

    • CBZ-D-proline [(R)-N-CBZ-proline]

    • (1R,4S)-1-Amino-4-hydroxymethyl-cyclopent-2-ene

  • Summary

Get PDF (115K)