Chapter 14. Bioinformatics

  1. Prof. Dr. Andreas Sebastian Bommarius1,
  2. Dr. Bettina R. Riebel2

Published Online: 28 JAN 2005

DOI: 10.1002/3527602364.ch14

Book Title

Biocatalysis

Biocatalysis

Additional Information

How to Cite

Bommarius, A. S. and Riebel, B. R. (2005) Bioinformatics, in Biocatalysis, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602364.ch14

Author Information

  1. 1

    School of Chemical and Biomolecular Engineering, Parker H. Petit Biotechnology Institute, Georgia Institute of Technology, 315 Ferst Drive, N. W. Atlanta, GA 30332-0363, USA

  2. 2

    Emory University School of Medicine, Whitehead Research Building, 615 Michael Street, Atlanta, GA 30322, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 28 JAN 2004

ISBN Information

Print ISBN: 9783527303441

Online ISBN: 9783527602360

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Keywords:

  • bioinformatics;
  • Protein Data Bank (PDB);
  • Protein Explorer;
  • ExPASy Server;
  • GenBank;
  • SwissProt;
  • dehydrogenases;
  • BLAST;
  • ClustalW;
  • phylogenetic tree

Summary

  • Starting Point: from Consequence (Function) to Sequence

    • Conventional Path: from Function to Sequence

    • Novel Path: from Sequence to Consequence (Function)

  • Bioinformatics: What is it, Why do we Need it, and Why Now? (NCBI Homepage)

    • What is Bioinformatics?

    • Why do we Need Bioinformatics?

    • Why Bioinformatics Now?

  • Tools of Bioinformatics: Databases, Alignments, Structural Mapping

    • Available Databases

    • Protein Data Bank (PDB)

    • Protein Explorer

    • ExPASy Server: Roche Applied Science Biochemical Pathways

    • GenBank

    • SwissProt

    • Information on an Enzyme: the Example of dehydrogenases

  • Applied Bioinformatics Tools, with Examples

    • BLAST

    • Aligning Several Protein Sequences using ClustalW

    • Task: Whole Genome Analysis

    • Phylogenetic Tree

  • Bioinformatics for Structural Information on Enzymes

    • The Status of Predicting Protein Three-Dimensional Structure

  • Conclusion and Outlook

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