Chapter 14. Nonviral Gene Transfer Systems in Somatic Gene Therapy
- Dr. Oliver Kayser,
- Prof. Dr. Rainer H. Müller
Published Online: 28 JAN 2005
DOI: 10.1002/3527602410.ch14
Copyright © 2004 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications
Additional Information
How to Cite
Kayser, O. and Kiderlen, A. F. (2005) Nonviral Gene Transfer Systems in Somatic Gene Therapy, in Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications (eds O. Kayser and R. H. Müller), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602410.ch14
Editor Information
Free University Berlin, Institute of Pharmacy, Pharmaceutical Technology, Biopharmacy & Biotechnology, Kelchstr. 31, 12169 Berlin, Germany
Publication History
- Published Online: 28 JAN 2005
- Published Print: 28 JAN 2004
ISBN Information
Print ISBN: 9783527305544
Online ISBN: 9783527602414
- Summary
- Chapter
Keywords:
- pharmaceutical biotechnology;
- nonviral gene transfer systems;
- somatic gene therapy;
- electroporation;
- bioballistics;
- chemical vectors;
- cationic liposomes (lipoplex);
- polymer particles (polyplex);
- poly-l-lysine (PLL) poly-l-arginine (PLA);
- polyethyleneimine (PEI);
- dendrimers;
- poly(2-dimethylamino)ethylmethacrylate
Summary
Introduction
What is Gene Therapy?
Strategies in Gene Therapy
Gene Transfer Systems
Physical Gene Transfer Systems
Electroporation
Bioballistics
Chemical Vectors
Cationic Liposomes (Lipoplex)
Polymer Particles (Polyplex)
Poly-L-Lysine (PLL) and Poly-L-Arginine (PLA)
Polyethyleneimine (PEI)
Dendrimers
Poly(2-dimethylamino)ethylmethacrylate
Outlook
References