Chapter 3. Biopharmaceuticals Expressed in Plants
- Dr. Oliver Kayser,
- Prof. Dr. Rainer H. Müller
Published Online: 28 JAN 2005
DOI: 10.1002/3527602410.ch3
Copyright © 2004 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications
Additional Information
How to Cite
Knäblein, J. (2005) Biopharmaceuticals Expressed in Plants, in Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications (eds O. Kayser and R. H. Müller), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602410.ch3
Editor Information
Free University Berlin, Institute of Pharmacy, Pharmaceutical Technology, Biopharmacy & Biotechnology, Kelchstr. 31, 12169 Berlin, Germany
Publication History
- Published Online: 28 JAN 2005
- Published Print: 28 JAN 2004
ISBN Information
Print ISBN: 9783527305544
Online ISBN: 9783527602414
- Summary
- Chapter
Keywords:
- pharmaceutical biotechnology;
- biopharmaceuticals expressed in plants;
- alternative expression systems;
- plant expression;
- SWOT analysis;
- risk assessment;
- contingency measures;
- glycosylation;
- tobacco;
- rhizosecretion;
- transfection;
- moss
Summary
Introduction
Alternative Expression Systems
History of Plant Expression
SWOT Analysis Reveals a Ripe Market for Plant Expression Systems
Risk Assessment and Contingency Measures
Moving Plants to Humanlike Glycosylation
Three Promising Examples: Tobacco (Rhizosecretion, Transfection) and Moss (Glycosylation)
Harnessing Tobacco Roots to Secrete Proteins
High Protein Yields Utilizing Viral Transfection
Simple Moss Performs Complex Glycosylation
Other Systems Used for Plant Expression
Analytical Characterization
Conclusion
Acknowledgments
References