Chapter 12. Synthetic Lipid A Antagonists for Sepsis Treatment

  1. Prof. Dr. Chi-Huey Wong
  1. William J. Christ,
  2. Lynn D. Hawkins,
  3. Michael D. Lewis,
  4. Yoshito Kishi

Published Online: 28 JAN 2005

DOI: 10.1002/3527602437.ch12

Book Title

Carbohydrate-Based Drug Discovery

Carbohydrate-Based Drug Discovery

Additional Information

How to Cite

Christ, W. J., Hawkins, L. D., Lewis, M. D. and Kishi, Y. (2005) Synthetic Lipid A Antagonists for Sepsis Treatment, in Carbohydrate-Based Drug Discovery (ed C.-H. Wong), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602437.ch12

Editor Information

  1. Ernest W. Hahn Chair in Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines RoadLa Jolla, CA 92037, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 26 AUG 2003

ISBN Information

Print ISBN: 9783527306329

Online ISBN: 9783527602438

SEARCH

CHAPTER TOOLS

Get PDF (312K)

Keywords:

  • synthetic lipid A antagonists;
  • sepsis treatment;
  • lipid X analogues;
  • monosaccharide antagonists;
  • disaccharide antagonists

Summary

  • Background

  • Hypothesis and Approach

    • Monosaccharide Antagonists: Lipid X Analogues

    • Disaccharide Antagonist of Lipid A: First Generation

    • Disaccharide Antagonist of Lipid A: Second Generation

  • Conclusion

  • Acknowledgement

  • References

Get PDF (312K)