Chapter 13. Polysialic Acid Vaccines

  1. Prof. Dr. Chi-Huey Wong
  1. Harold J. Jennings

Published Online: 28 JAN 2005

DOI: 10.1002/3527602437.ch13

Book Title

Carbohydrate-Based Drug Discovery

Carbohydrate-Based Drug Discovery

Additional Information

How to Cite

Jennings, H. J. (2005) Polysialic Acid Vaccines, in Carbohydrate-Based Drug Discovery (ed C.-H. Wong), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602437.ch13

Editor Information

  1. Ernest W. Hahn Chair in Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines RoadLa Jolla, CA 92037, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 26 AUG 2003

ISBN Information

Print ISBN: 9783527306329

Online ISBN: 9783527602438

SEARCH

CHAPTER TOOLS

Get PDF (1062K)

Keywords:

  • polysialic acid vaccines;
  • group C meningococcal vaccines;
  • group B meningococcal vaccines;
  • chemically modified group B meningococcal vaccines;
  • cancer vaccines

Summary

  • Introduction

  • Group C Meningococcal Vaccines

    • Structure and Immunology of GCMP

    • Group C Conjugate Vaccines

  • Group B Meningococcal Vaccines

    • Structure of GBMP

    • Immunology of GBMP

    • B Polysaccharide-Protein Conjugates

    • Extended Helical Epitope of PSA

  • Chemically Modified Group B Meningococcal Vaccines

    • N-Propionylated PSA Conjugate Vaccine

    • Immunology of NPr PSA

    • Protective Epitope mimicked by NPr PSA

    • Safety Concerns

  • Cancer Vaccines

    • PSA on Human Cells

    • Potential of NPr PSA as a Cancer Vaccine

  • Acknowledgements

  • References

Get PDF (1062K)