Chapter 24. RNA-Aminoglycoside Interactions

  1. Prof. Dr. Chi-Huey Wong
  1. Haim Weizman,
  2. Yitzhak Tor

Published Online: 28 JAN 2005

DOI: 10.1002/3527602437.ch24

Book Title

Carbohydrate-Based Drug Discovery

Carbohydrate-Based Drug Discovery

Additional Information

How to Cite

Weizman, H. and Tor, Y. (2005) RNA-Aminoglycoside Interactions, in Carbohydrate-Based Drug Discovery (ed C.-H. Wong), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602437.ch24

Editor Information

  1. Ernest W. Hahn Chair in Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines RoadLa Jolla, CA 92037, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 26 AUG 2003

ISBN Information

Print ISBN: 9783527306329

Online ISBN: 9783527602438

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CHAPTER TOOLS

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Keywords:

  • RNA-aminoglycoside interactions;
  • RNA;
  • emerging therapeutic target;
  • aminoglycoside antibiotics;
  • RNA targets;
  • binding assays;
  • dimeric aminoglycosides;
  • aminoglycoside-intercalator conjugates;
  • guanidinoglycosides

Summary

  • RNA as an Emerging Therapeutic Target

  • Aminoglycoside Antibiotics: Past and Present

  • Aminoglycosides as RNA Binders

  • Identifying RNA Targets and Developing Binding Assays

  • Dimeric Aminoglycosides

  • Aminoglycoside-Intercalator Conjugates

  • Guanidinoglycosides

  • Summary and Outlook

  • Acknowledgements

  • References

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