Chapter 27. Neoglycolipids: Identification of Functional Carbohydrate Epitopes

  1. Prof. Dr. Chi-Huey Wong
  1. Ten Feizi,
  2. Alexander M. Lawson,
  3. Wengang Chai

Published Online: 28 JAN 2005

DOI: 10.1002/3527602437.ch27

Carbohydrate-Based Drug Discovery

Carbohydrate-Based Drug Discovery

How to Cite

Feizi, T., Lawson, A. M. and Chai, W. (2005) Neoglycolipids: Identification of Functional Carbohydrate Epitopes, in Carbohydrate-Based Drug Discovery (ed C.-H. Wong), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602437.ch27

Editor Information

  1. Ernest W. Hahn Chair in Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines RoadLa Jolla, CA 92037, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 26 AUG 2003

ISBN Information

Print ISBN: 9783527306329

Online ISBN: 9783527602438

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Keywords:

  • neoglycolipids;
  • identification of functional carbohydrate epitopes;
  • developing neoglycolipids as oligosaccharide probes;
  • mass spectrometry;
  • scope of the neoglycolipid technology;
  • oligosaccharide microarrays

Summary

  • Rationale for Developing Neoglycolipids as Oligosaccharide Probes

  • The First and Second Generation Neoglycolipids

  • Mass Spectrometry of Neoglycolipids

  • Scope of the Neoglycolipid Technology

    • Novel Sulfated Ligands for the Selectins

    • Novel Class of O-Glycans (O-Mannosyl) in the Brain

    • Unique Tetrasaccharide Sequence on Heparan Sulfate

  • Oligosaccharide Microarrays

  • Summary and Perspectives

  • Acknowledgement

  • References