Chapter 33. Modified and Modifying Sugars as a New Tool for the Development of Therapeutic Agents – Glycosidated Phospholipids as a New Type of Antiproliferative Agents

  1. Prof. Dr. Chi-Huey Wong
  1. Kerstin Danker,
  2. Annette Fischer,
  3. Werner Reutter

Published Online: 28 JAN 2005

DOI: 10.1002/3527602437.ch33

Book Title

Carbohydrate-Based Drug Discovery

Carbohydrate-Based Drug Discovery

Additional Information

How to Cite

Danker, K., Fischer, A. and Reutter, W. (2005) Modified and Modifying Sugars as a New Tool for the Development of Therapeutic Agents – Glycosidated Phospholipids as a New Type of Antiproliferative Agents, in Carbohydrate-Based Drug Discovery (ed C.-H. Wong), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602437.ch33

Editor Information

  1. Ernest W. Hahn Chair in Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines RoadLa Jolla, CA 92037, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 26 AUG 2003

ISBN Information

Print ISBN: 9783527306329

Online ISBN: 9783527602438

SEARCH

CHAPTER TOOLS

Get PDF (257K)

Keywords:

  • modified sugars;
  • modifying sugars;
  • glycosidated phospholipids as a new type of antiproliferative agents;
  • effect on cell matrix adhesion

Summary

  • Introduction

  • Structures of Synthetic Glycosidated Phospholipid Analogues

  • Antiproliferative Effect and Cytotoxicity of Glycosidated Phospholipid Analogues in Cell Culture Systems

  • Effect of Glycosidated Phospholipid Analogues on Cell Matrix Adhesion

  • Mechanisms of Action

  • Outlook and New Developments

  • Acknowledgements

  • References

Get PDF (257K)