Chapter 17. Genetic and Biochemical Analysis of the Biosynthesis of the Orange Carotenoid Staphyloxanthin of Staphylococcus aureus

  1. Volkmar Braun1,
  2. Friedrich Götz2
  1. Friedrich Götz

Published Online: 28 JAN 2005

DOI: 10.1002/3527602720.ch17

Book Title

Microbial Fundamentals of Biotechnology

Microbial Fundamentals of Biotechnology

Additional Information

How to Cite

Götz, F. (2005) Genetic and Biochemical Analysis of the Biosynthesis of the Orange Carotenoid Staphyloxanthin of Staphylococcus aureus, in Microbial Fundamentals of Biotechnology (eds V. Braun and F. Götz), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602720.ch17

Editor Information

  1. 1

    Mikrobiologie/Membranphysiologie, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany

  2. 2

    Mikrobielle Genetik, Universität Tübingen, Waldhäuser Str. 70/8, D-72076 Tübingen, Germany

Author Information

  1. Mikrobielle Genetik, Universität Tübingen, Waldhäuser Str. 70/8, D-72076 Tübingen, Germany

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 29 NOV 2001

ISBN Information

Print ISBN: 9783527306152

Online ISBN: 9783527602728

SEARCH

CHAPTER TOOLS

Get PDF (85K)

Keywords:

  • carotenoid staphyloxanthin;
  • biosynthesis;
  • Staphylococcus aureus;
  • carotenoid biosynthetic genes;
  • cloning;
  • identification;
  • squalene

Summary

This chapter contains sections titled:

  • Introduction

  • Cloning of the carotenoid biosynthetic genes from S. aureus Newman in S. carnosus and E. coli

  • Function of CrtM and CrtN

  • Identification of carotenoids in S. carnosus (pOC21), E. coli (pUG1), and S. aureus Newman

  • Identification of dehydrosqualene in E. coli (pUG1) and E. coli (UG9)

  • Squalene is very likely no substrate for CrtN, the proposed dehydrosqualene desaturase

  • The crt operon

  • Homology of CrtO, CrtP, and CrtQ

  • Construction of crtM mutants of S. aureus strain Newman

  • σB-regulated promoter of the crt operon from S. aureus strain Newman

  • The carotenoid biosynthesis genes

  • Function of the pigments in S. aureus strain Newman

  • Distribution of pigment biosynthesis genes among staphylococcal species

  • References

Get PDF (85K)