Chapter 3. Biosynthesis of the Lantibiotics Epidermin and Gallidermin
- Volkmar Braun2,
- Friedrich Götz3
Published Online: 28 JAN 2005
DOI: 10.1002/3527602720.ch3
Copyright © 2001 Wiley-VCH Verlag GmbH
Book Title
Microbial Fundamentals of Biotechnology
Additional Information
How to Cite
Götz, F. and Jung, G. (2005) Biosynthesis of the Lantibiotics Epidermin and Gallidermin, in Microbial Fundamentals of Biotechnology (eds V. Braun and F. Götz), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602720.ch3
Editor Information
- 2
Mikrobiologie/Membranphysiologie, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany
- 3
Mikrobielle Genetik, Universität Tübingen, Waldhäuser Str. 70/8, D-72076 Tübingen, Germany
Publication History
- Published Online: 28 JAN 2005
- Published Print: 29 NOV 2001
ISBN Information
Print ISBN: 9783527306152
Online ISBN: 9783527602728
- Summary
- Chapter
Keywords:
- lantibiotics;
- epidermin;
- gallidermin;
- biosynthesis;
- immunity genes;
- epidermin leader peptidase EpiP;
- flavoenzyme EpiD
Summary
This chapter contains sections titled:
History of lantibiotics and lantibiotic research in Tübingen
Primary structure and proposed maturation of epidermin in staphylococci
Genetic organization and regulation of the epidermin genes
Isolation and characterization of genetically engineered gallidermin and epidermin analogues
Function of the epidermin immunity genes epiFEG
Inactivation and characterization of the epidermin leader peptidase EpiP
The flavoenzyme EpiD and formation of peptidyl-aminoenethiolates
Incorporation of d-alanine into S. aureus teichoic acids confers resistance to defensins, protegrins, and other antimicrobial peptides
Conclusions
References