Chapter 7. Complex networks in genomics and proteomics

  1. Stefan Bornholdt3 and
  2. Hans Georg Schuster4
  1. Ricard V. Solé1 and
  2. Romualdo Pastor-Satorras2

Published Online: 28 JAN 2005

DOI: 10.1002/3527602755.ch7

Handbook of Graphs and Networks: From the Genome to the Internet

Handbook of Graphs and Networks: From the Genome to the Internet

How to Cite

Solé, R. V. and Pastor-Satorras, R. (2002) Complex networks in genomics and proteomics, in Handbook of Graphs and Networks: From the Genome to the Internet (eds S. Bornholdt and H. G. Schuster), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527602755.ch7

Editor Information

  1. 3

    University of Leipzig, Germany

  2. 4

    University of Kiel, Germany

Author Information

  1. 1

    ICREA-Complex Systems Lab, Universitat Pompeu Fabra-IMIM, Dr Aiguader 80, 08003 Barcelona, Spain

  2. 2

    Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya, Campus Nord B4, 08034 Barcelona, Spain

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 8 NOV 2002

ISBN Information

Print ISBN: 9783527403363

Online ISBN: 9783527602759

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Keywords:

  • complex networks;
  • genomics;
  • proteomics;
  • cellular networks;
  • gene duplication models;
  • numerical simulations

Summary

  • Introduction

  • Cellular networks

    • Two-gene networks

    • Random networks

  • Three interconnected levels of cellular nets

  • Small world graphs and scale-free nets

  • Scale-free proteomes: gene duplication models

    • Mean-field rate equation for the average connectivity

    • Rate equation for the node distribution nk

    • Numerical simulations

  • Discussion

  • References