Chapter 1. Recent Advances in the Synthesis of Cyclic Polyether Marine Natural Products

  1. Yves Chapleur
  1. K. C. Nicolaou1,2,
  2. M. H. D. Postema1,2,
  3. N. D. Miller1,2

Published Online: 28 JAN 2005

DOI: 10.1002/3527603239.ch1

Book Title

Carbohydrate Mimics: Concepts and Methods

Carbohydrate Mimics: Concepts and Methods

Additional Information

How to Cite

Nicolaou, K. C., Postema, M. H. D. and Miller, N. D. (2005) Recent Advances in the Synthesis of Cyclic Polyether Marine Natural Products, in Carbohydrate Mimics: Concepts and Methods (ed Y. Chapleur), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603239.ch1

Editor Information

  1. UMR CNRS 7565, Université Henri Poincaré-Nancy I, BP239, F-54506 Vandceuvre, France

Author Information

  1. 1

    Department of Chemistry and The Skaggs Inst. of Chemical Biology, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, USA

  2. 2

    Dept. of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 12 NOV 1997

ISBN Information

Print ISBN: 9783527295265

Online ISBN: 9783527603237

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Keywords:

  • carbohydrate mimics;
  • cyclic polyether marine natural products;
  • cyclic ethers;
  • brevetoxin B;
  • polyether synthesis

Summary

  • Introduction

  • Synthetic Technology for the Construction of Cyclic Ethers

  • Total Synthesis of Brevetoxin B

  • Recent Developments in Polyether Synthesis

    • Radical-Based Reduction of Thionolactones to Cyclic Ethers

    • Synthesis of 1,1′-Bistetrahydropyran Systems via Copper(I)-Promoted Stille Coupling

    • The Olefin Metathesis Approach to Cyclic Enol Ether Construction

  • Conclusion

  • References

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