Chapter 25. Design and Synthesis of Potential Fucosyl Transferase Inhibitors

  1. Yves Chapleur
  1. G. A. van der Marel1,
  2. B. M. Heskamp1,
  3. G. H. Veeneman2,
  4. C. A. A. van Boeckel2,
  5. J. H. van Boom1

Published Online: 28 JAN 2005

DOI: 10.1002/3527603239.ch25

Book Title

Carbohydrate Mimics: Concepts and Methods

Carbohydrate Mimics: Concepts and Methods

Additional Information

How to Cite

van der Marel, G. A., Heskamp, B. M., Veeneman, G. H., van Boeckel, C. A. A. and van Boom, J. H. (2005) Design and Synthesis of Potential Fucosyl Transferase Inhibitors, in Carbohydrate Mimics: Concepts and Methods (ed Y. Chapleur), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603239.ch25

Editor Information

  1. UMR CNRS 7565, Université Henri Poincaré-Nancy I, BP239, F-54506 Vandceuvre, France

Author Information

  1. 1

    Leiden Institute of Chemistry, Gorlaeus Laboratory, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands

  2. 2

    N.V. Organon, P.O. Box 20, 5340 BH Oss, The Netherlands

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 12 NOV 1997

ISBN Information

Print ISBN: 9783527295265

Online ISBN: 9783527603237

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CHAPTER TOOLS

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Keywords:

  • fucosyl transferase inhibitors;
  • selectins;
  • leucocyte extravasation;
  • adhesion inhibition;
  • fucosyltransferase inhibitors

Summary

  • Introduction

    • Role of Selectins in Leucocyte Extravasation

  • Receptor-based Adhesion Inhibition

    • Ligand-based Adhesion Inhibition

    • Fucosyltransferase inhibitors

  • Conclusion

  • References

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