Chapter 28. Nucleosides and Nucleotides Containing 5-Alkyl Pyrimidines. Chemistry and Molecular Pharmacology

  1. Yves Chapleur
  1. L. Ötvös

Published Online: 28 JAN 2005

DOI: 10.1002/3527603239.ch28

Book Title

Carbohydrate Mimics: Concepts and Methods

Carbohydrate Mimics: Concepts and Methods

Additional Information

How to Cite

Ötvös, L. (2005) Nucleosides and Nucleotides Containing 5-Alkyl Pyrimidines. Chemistry and Molecular Pharmacology, in Carbohydrate Mimics: Concepts and Methods (ed Y. Chapleur), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603239.ch28

Editor Information

  1. UMR CNRS 7565, Université Henri Poincaré-Nancy I, BP239, F-54506 Vandceuvre, France

Author Information

  1. Central Research Institute for Chemistry, Hungarian Academy of Sciences, H-1525. Budapest, P.O. Box 17. Hungary

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 12 NOV 1997

ISBN Information

Print ISBN: 9783527295265

Online ISBN: 9783527603237

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CHAPTER TOOLS

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Keywords:

  • nucleosides;
  • nucleotides;
  • 5-alkyl pyrimidines;
  • polymerase;
  • polynucleotides;
  • 5-alkyl-2′-deoxyuridines;
  • 5-isopropyl-2′-deoxyuridine;
  • oligonucleotides

Summary

  • Chemistry

    • Synthetic Methods

    • Deacylation of Derivatives in the Sugar Moiety

  • Bioorganic Chemistry

    • Substrate Specificity in Polymerase Catalysed Reactions

      • 5-n-Alkyl-, 5-(n-1-alkenyl)- and 5-(n-1-alkynyl)dUTPs

      • Deoxyuridines Containing Branched Substituents in Position 5

    • Structural Properties and Stability of Polynucleotides Containing 5-Alkyl-2′-deoxyuridines

  • Molecular Pharmacology

    • Molecular Pharmacology of the Antiherpetic Activity of 5-Isopropyl-2′-deoxyuridine

    • Antisense Drug Properties of Oligonucleotides Containing 5-Alkyl-2′-deoxyuridines

  • References

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