Chapter 29. Anhydrohexitols as Conformationally Constrained Furanose Mimics, Design of an RNA-Receptor

  1. Yves Chapleur
  1. P. Herdewijn

Published Online: 28 JAN 2005

DOI: 10.1002/3527603239.ch29

Carbohydrate Mimics: Concepts and Methods

Carbohydrate Mimics: Concepts and Methods

How to Cite

Herdewijn, P. (2005) Anhydrohexitols as Conformationally Constrained Furanose Mimics, Design of an RNA-Receptor, in Carbohydrate Mimics: Concepts and Methods (ed Y. Chapleur), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603239.ch29

Editor Information

  1. UMR CNRS 7565, Université Henri Poincaré-Nancy I, BP239, F-54506 Vandceuvre, France

Author Information

  1. Rega Institute, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium

Publication History

  1. Published Online: 28 JAN 2005
  2. Published Print: 12 NOV 1997

ISBN Information

Print ISBN: 9783527295265

Online ISBN: 9783527603237

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Keywords:

  • anhydrohexitols;
  • furanose;
  • RNA-receptor;
  • oligonucleotides;
  • 2′,3′-dideoxy-3′-C-hydroxymethyl-α-l-threo-pentopyranosyl nucleoside;
  • 1,5-anhydro-2,3-dideoxy-d-arabino-hexitol nucleoside;
  • six-membered carbohydrate-like moiety

Summary

  • Introduction

  • Double Stranded RNA Structure

  • Design of Oligonucleotides with a Six Membered Carbohydrate Moiety

  • Synthesis of 2′,3′-Dideoxy-3′-C-Hydroxymethyl-α-l-threo-Pentopyranosyl Nucleoside and 1,5-Anhydro-2,3-Dideoxy-d-arabino-Hexitol Nucleoside

  • Oligonucleotide Built up from Nucleosides with a Six-membered Carbohydrate-like Moiety

  • 1,5-Anhydrohexitol Nucleoside as a Mimic of a Furanose Nucleoside in its 2′-endo/3′-exo Conformation

  • References