Chapter 1. Basic Principles

  1. Dr. E. Klipp,
  2. Dr. R. Herwig,
  3. Dr. A. Kowald,
  4. C. Wierling,
  5. Prof. Dr. H. Lehrach

Published Online: 11 MAY 2005

DOI: 10.1002/3527603603.ch1

Book Title

Systems Biology in Practice: Concepts, Implementation and Application

Systems Biology in Practice: Concepts, Implementation and Application

Additional Information

How to Cite

Klipp, E., Herwig, R., Kowald, A., Wierling, C. and Lehrach, H. (2005) Basic Principles, in Systems Biology in Practice: Concepts, Implementation and Application, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603603.ch1

Author Information

  1. MPI für Molekulare Genetik, Ihnestraße 73, 14195 Berlin, Germany

Publication History

  1. Published Online: 11 MAY 2005
  2. Published Print: 17 FEB 2005

ISBN Information

Print ISBN: 9783527310784

Online ISBN: 9783527603602

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CHAPTER TOOLS

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Keywords:

  • systems biology;
  • modeling;
  • properties of models;
  • data integration

Summary

This chapter contains sections titled:

  • Systems Biology is Biology!

  • Systems Biology is Modeling

    • Properties of Models

      • Model Assignment is not Unique

      • System State

      • Steady States

      • Variables, Parameters, and Constants

      • Model Behavior

      • Process Classification

      • Purpose and Adequateness of Models

      • Advantages of Computational Modeling

      • Model Development

    • Typical Aspects of Biological Systems and Corresponding Models

      • Network Versus Elements

      • Modularity

      • Robustness and Sensitivity are Two Sides of the Same Coin

  • Systems Biology is Data Integration

  • Systems Biology is a Living Science

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