Chapter 14. Comparative Fermentation

  1. Prof. Dr. Gerd Gellissen3,4
  1. Stephan Hellwig1,3,
  2. Christoph Stöckmann2,
  3. Prof. Dr. Gerd Gellissen3,4,
  4. Jochen Büchs2

Published Online: 19 MAY 2005

DOI: 10.1002/3527603670.ch14

Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems

Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems

How to Cite

Hellwig, S., Stöckmann, C., Gellissen, G. and Büchs, J. (2005) Comparative Fermentation, in Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems (ed G. Gellissen), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603670.ch14

Editor Information

  1. 3

    MedArtis Pharmaceuticals GmbH, Pauwelsstr. 19, 52047 Aachen, Germany

  2. 4

    Ringstrasse 30, 42489 Wülfrath, Germany

Author Information

  1. 1

    Fraunhofer Institute for Molecular Biology and Ecology (IME), Worringerweg 1, 52074 Aachen, Germany

  2. 2

    Biochemical Engineering, RWTH Aachen University, Worringer Weg 1, 52056 Aachen, Germany

  3. 3

    MedArtis Pharmaceuticals GmbH, Pauwelsstr. 19, 52047 Aachen, Germany

  4. 4

    Ringstrasse 30, 42489 Wülfrath, Germany

Publication History

  1. Published Online: 19 MAY 2005
  2. Published Print: 4 NOV 2004

ISBN Information

Print ISBN: 9783527310364

Online ISBN: 9783527603671

SEARCH

Keywords:

  • production of recombinant proteins;
  • novel microbial and eucaryotic expression systems;
  • comparative fermentation;
  • Escherichia coli;
  • Staphylococcus carnosus;
  • Arxula adeninivorans;
  • Hansenula polymorpha;
  • Sordaria macrospora;
  • media and fermentation strategies;
  • development of media and strategies for submerged cultivation

Summary

This chapter contains sections titled:

  • Introduction

  • Escherichia coli

    • Media and Fermentation Strategies

    • Downstream Processing

    • Case Study: Production of GFP in a Medium Cell Density Fermentation of E. coli

  • Staphylococcus carnosus

    • Media and Fermentation Strategies

  • Arxula adeninivorans

    • Current Status of Media and Fermentation Strategies

    • Development of Media and Fermentation Strategies

    • Case Study: Production of Heterologous Phytase in Shake-flask Cultures and a High-cell- density, Fed-batch Fermentation of A. adeninivorans

  • Hansenula polymorpha

    • Media and Fermentation Strategies

    • Downstream Processing

    • Case Study: Production of a Secreted Protein in H. polymorpha

  • Sordaria macrospora

    • Current Status of Media and Fermentation Strategies

    • Development of Media and Strategies for Submerged Cultivation

  • Appendix

    • Escherichia coli Media

    • Staphylococcus carnosus Media

    • Yeast Media

    • Sordaria macrospora Media

  • References