Chapter 4. Staphylococcus carnosus and other Gram-Positive Bacteria
- Prof. Dr. Gerd Gellissen2,3
Published Online: 19 MAY 2005
DOI: 10.1002/3527603670.ch4
Copyright © 2005 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems
Additional Information
How to Cite
Freudl, R. (2005) Staphylococcus carnosus and other Gram-Positive Bacteria, in Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems (ed G. Gellissen), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603670.ch4
Editor Information
- 2
MedArtis Pharmaceuticals GmbH, Pauwelsstr. 19, 52047 Aachen, Germany
- 3
Ringstrasse 30, 42489 Wülfrath, Germany
Publication History
- Published Online: 19 MAY 2005
- Published Print: 4 NOV 2004
ISBN Information
Print ISBN: 9783527310364
Online ISBN: 9783527603671
- Summary
- Chapter
Keywords:
- production of recombinant proteins;
- novel microbial and eucaryotic expression systems;
- Staphylococcus carnosus and other Gram-positive bacteria;
- major protein export routes;
- extracytosolic protein folding;
- the cell wall as a barrier for the secretion;
- degradation of exported proteins;
- cell-associated and secreted proteases
Summary
This chapter contains sections titled:
Introduction
Major Protein Export Routes in Gram-positive Bacteria
The General Secretion (Sec) Pathway
The Twin-Arginine Translocation (Tat) Pathway
Secretion Signals
Extracytosolic Protein Folding
The Cell Wall as a Barrier for the Secretion of Heterologous Proteins
Degradation of Exported Proteins by Cell-associated and Secreted Proteases
Staphylococcus carnosus
General Description
Microbiological and Molecular Biological Tools
S. carnosus as Host Organism for the Analysis of Staphylococcal-related Pathogenicity Aspects
Secretory Production of Heterologous Proteins by S. carnosus
The Staphylococcus hyicus Lipase: Secretory Signals and Heterologous Expression in S. carnosus
Use of the Pre-pro-part of the S. hyicus Lipase for the Secretion of Heterologous Proteins in S. carnosus
Process Development for the Secretory Production of a Human Calcitonin Precursor Fusion Protein by S. carnosus
Surface Display on S. carnosus
Appendix
References