Chapter 1.6. Biosynthesis of β-Amino Acids

  1. Professor Dr. Carsten Schmuck3 and
  2. Professor Dr. Helma Wennemers4
  1. Peter Spiteller1 and
  2. Franz von Nussbaum2

Published Online: 27 MAY 2005

DOI: 10.1002/3527603727.ch1f

Highlights in Bioorganic Chemistry: Methods and Applications

Highlights in Bioorganic Chemistry: Methods and Applications

How to Cite

Spiteller, P. and von Nussbaum, F. (2004) Biosynthesis of β-Amino Acids, in Highlights in Bioorganic Chemistry: Methods and Applications (eds C. Schmuck and H. Wennemers), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603727.ch1f

Editor Information

  1. 3

    Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

  2. 4

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Author Information

  1. 1

    Institut für Organische Chemie und Biochemie, Technische Universität München, Lichtenbergstraße 4, 85747 Garching, Germany

  2. 2

    Bayer AG, Pharma Research PH-R-EU-CR, Geb. 460/3, 42096 Wuppertal, Germany

Publication History

  1. Published Online: 27 MAY 2005
  2. Published Print: 14 JAN 2004

ISBN Information

Print ISBN: 9783527306565

Online ISBN: 9783527603725

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Keywords:

  • biomolecules;
  • conformation;
  • biosynthesis of β-amino acids

Summary

This chapter contains sections titled:

    • Introduction

    • Biosynthesis of β-Amino Acids by Catabolic Pathways

      • β-Alanine

      • Biosynthesis of β-Alanine from Uracil

      • Biosynthesis of β-Alanine from l-Aspartic Acid

      • Biosynthesis of β-Alanine from Spermidine and Spermine

      • (R) - and (S) -β-Aminoisobutyrate

    • Biosynthesis of β-Amino Acids by Aminomutases

      • (S)-β-Lysine

      • Properties of the Enzyme

      • Stereochemical Aspects

      • Reaction Mechanism

      • (R)-β-Leucine

      • (S)-β-Arginine

      • (R)-β-Phenylalanine

      • β-Tyrosine

    • Other Aminomutases

      • β-Lysine 5,6-Aminomutase (D-Lysine 5,6-Aminomutase)

      • D-Ornithine 4,5-Aminomutase

    • Discussion

    • Dedication

    • Acknowledgment

    • References