Chapter 2.6. Interaction of Nitrogen Monoxide and Peroxynitrite with Hemoglobin and Myoglobin

  1. Professor Dr. Carsten Schmuck2 and
  2. Professor Dr. Helma Wennemers3
  1. Susanna Herold

Published Online: 27 MAY 2005

DOI: 10.1002/3527603727.ch2f

Highlights in Bioorganic Chemistry: Methods and Applications

Highlights in Bioorganic Chemistry: Methods and Applications

How to Cite

Herold, S. (2004) Interaction of Nitrogen Monoxide and Peroxynitrite with Hemoglobin and Myoglobin, in Highlights in Bioorganic Chemistry: Methods and Applications (eds C. Schmuck and H. Wennemers), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603727.ch2f

Editor Information

  1. 2

    Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

  2. 3

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Author Information

  1. Laboratorium für Anorganische Chemie, Eidgenössische Technische Hochschule ETH Hönggerberg, 8093 Zürich, Switzerland

Publication History

  1. Published Online: 27 MAY 2005
  2. Published Print: 14 JAN 2004

ISBN Information

Print ISBN: 9783527306565

Online ISBN: 9783527603725

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Keywords:

  • non-covalent intermolecular interactions;
  • interaction of nitrogen monoxide and peroxynitrite with hemoglobin and myoglobin

Summary

This chapter contains sections titled:

    • Biosynthesis, Reactivity, and Physiological Functions of Nitrogen Monoxide

      • The Biological Chemistry of Peroxynitrite

    • Interaction of Nitrogen Monoxide and Peroxynitrite with Hemoglobin and Myoglobin

      • The NO⋅-mediated Oxidation of Oxymyoglobin and Oxyhemoglobin

      • The Peroxynitrite-mediated Oxidation of OxyMb and OxyHb

    • NO⋅ as an Antioxidant

      • The NO⋅-mediated Reduction of FerrylMb and FerrylHb

    • Conclusion: A New Function of Myoglobin?

    • References

    • Hemoglobin and Myoglobin