Chapter 3.1. Building a Bridge between Chemistry and Biology — Molecular Forceps That Inhibit the Farnesylation of RAS

  1. Professor Dr. Carsten Schmuck2 and
  2. Professor Dr. Helma Wennemers3
  1. Hans Peter Nestler1 and
  2. Professor Dr. Helma Wennemers3

Published Online: 27 MAY 2005

DOI: 10.1002/3527603727.ch3a

Highlights in Bioorganic Chemistry: Methods and Applications

Highlights in Bioorganic Chemistry: Methods and Applications

How to Cite

Nestler, H. P. and Wennemers, H. (2004) Building a Bridge between Chemistry and Biology — Molecular Forceps That Inhibit the Farnesylation of RAS, in Highlights in Bioorganic Chemistry: Methods and Applications (eds C. Schmuck and H. Wennemers), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603727.ch3a

Editor Information

  1. 2

    Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

  2. 3

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Author Information

  1. 1

    Aventis Pharma Germany, Industrial Park Hoechst, Building G 879, 65926 Frankfurt am Main, Germany

  2. 3

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Publication History

  1. Published Online: 27 MAY 2005
  2. Published Print: 14 JAN 2004

ISBN Information

Print ISBN: 9783527306565

Online ISBN: 9783527603725

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Keywords:

  • studies in drug developments;
  • farnesylation of RAS;
  • split-and-mix libraries

Summary

This chapter contains sections titled:

    • Prolog

    • RAS — The Good, The Bad and The Ugly

    • Bridging the Gap

    • Epilog

    • References

    • Split-and-mix Libraries