Chapter 4.1. Selectivity of DNA Replication

  1. Professor Dr. Carsten Schmuck3 and
  2. Professor Dr. Helma Wennemers4
  1. Andreas Marx1,
  2. Daniel Summerer1,
  3. Michael Strerath1 and
  4. Susanne Brakmann2

Published Online: 27 MAY 2005

DOI: 10.1002/3527603727.ch4a

Highlights in Bioorganic Chemistry: Methods and Applications

Highlights in Bioorganic Chemistry: Methods and Applications

How to Cite

Marx, A., Summerer, D., Strerath, M. and Brakmann, S. (2004) Selectivity of DNA Replication, in Highlights in Bioorganic Chemistry: Methods and Applications (eds C. Schmuck and H. Wennemers), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603727.ch4a

Editor Information

  1. 3

    Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

  2. 4

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Author Information

  1. 1

    Kekulé-Institut für Organische Chemie und Biochemie, Universität Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany

  2. 2

    Institut für Zoologie, Universität Leipzig, Liebigstraße 18, Germany

Publication History

  1. Published Online: 27 MAY 2005
  2. Published Print: 14 JAN 2004

ISBN Information

Print ISBN: 9783527306565

Online ISBN: 9783527603725



  • studies in diagnostic developments;
  • selectivity of DNA replication;
  • polynucleotide polymerases


This chapter contains sections titled:

    • Introduction

    • Biochemical and Structural Studies

    • Use of Tailored Nucleotide Analogs to Probe DNA Polymerases

      • Non-polar Nucleobase Surrogates

      • Analogs with Modified Sugar Moieties

    • Conclusions and Perspectives

    • References

    • Polynucleotide Polymerases