Chapter 5.1. Protease-Catalyzed Formation of C[BOND]N Bonds

  1. Professor Dr. Carsten Schmuck2 and
  2. Professor Dr. Helma Wennemers3
  1. Frank Bordusa

Published Online: 27 MAY 2005

DOI: 10.1002/3527603727.ch5a

Highlights in Bioorganic Chemistry: Methods and Applications

Highlights in Bioorganic Chemistry: Methods and Applications

How to Cite

Bordusa, F. (2004) Protease-Catalyzed Formation of C[BOND]N Bonds, in Highlights in Bioorganic Chemistry: Methods and Applications (eds C. Schmuck and H. Wennemers), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603727.ch5a

Editor Information

  1. 2

    Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

  2. 3

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Author Information

  1. Max-Planck Society, Research Unit “Enzymology of Protein Folding”, Weinbergweg 22, 06120 Halle/Saale, Germany

Publication History

  1. Published Online: 27 MAY 2005
  2. Published Print: 14 JAN 2004

ISBN Information

Print ISBN: 9783527306565

Online ISBN: 9783527603725

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Keywords:

  • catalysis;
  • protease-catalyzed formation of C[BOND]N bonds

Summary

This chapter contains sections titled:

    • Optimization of Proteases for Synthesis: Selection of Current Techniques

    • Substrate Engineering

    • Classical Concept of Leaving-group Manipulation

    • Substrate Mimetics-mediated Syntheses

    • Enzyme Engineering

    • Chemical Enzyme Modifications

    • Genetic Enzyme Modifications

    • Conclusions

    • References