Chapter 5.2. Twin Ribozymes

  1. Professor Dr. Carsten Schmuck2 and
  2. Professor Dr. Helma Wennemers3
  1. Sabine Müller,
  2. Rüdiger Welz,
  3. Sergei A. Ivanov and
  4. Katrin Bossmann

Published Online: 27 MAY 2005

DOI: 10.1002/3527603727.ch5b

Highlights in Bioorganic Chemistry: Methods and Applications

Highlights in Bioorganic Chemistry: Methods and Applications

How to Cite

Müller, S., Welz, R., Ivanov, S. A. and Bossmann, K. (2004) Twin Ribozymes, in Highlights in Bioorganic Chemistry: Methods and Applications (eds C. Schmuck and H. Wennemers), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603727.ch5b

Editor Information

  1. 2

    Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

  2. 3

    Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland

Author Information

  1. Ruhr-Universität Bochum, Fakultät für Chemie, 44780 Bochum, Germany

Publication History

  1. Published Online: 27 MAY 2005
  2. Published Print: 14 JAN 2004

ISBN Information

Print ISBN: 9783527306565

Online ISBN: 9783527603725

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Keywords:

  • catalysis;
  • twin ribozymes;
  • ribozymes;
  • RNA as a catalyst

Summary

This chapter contains sections titled:

    • Introduction

    • Application of Ribozymes

    • Building Blocks for Twin Ribozymes

      • The Conventional Hairpin Ribozyme (HP-WT)

      • The Reverse-joined Hairpin Ribozyme (HP-RJ)

      • Three-way Junction Hairpin Ribozymes (HP-TJ)

      • Branched Reverse-joined Hairpin Ribozymes (HP-RJBR)

    • Design, Synthesis and Characterization of Twin Ribozymes

    • Application of Twin Ribozymes

    • Summary and Outlook

    • References

    • Ribozymes