Chapter 10. Single Biomolecule Manipulation for Bioelectronics

  1. Prof. Dr. Itamar Willner and
  2. Dr. Eugenii Katz
  1. Yoshiharu Ishii1 and
  2. Toshio Yanagida2

Published Online: 23 MAY 2005

DOI: 10.1002/352760376X.ch10

Bioelectronics: From Theory to Applications

Bioelectronics: From Theory to Applications

How to Cite

Ishii, Y. and Yanagida, T. (2005) Single Biomolecule Manipulation for Bioelectronics, in Bioelectronics: From Theory to Applications (eds I. Willner and E. Katz), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/352760376X.ch10

Editor Information

  1. The Hebrew University of Jerusalem, Institute of Chemistry, Givat Ram, Jerusalem 91904, Israel

Author Information

  1. 1

    Japan Science and Technology Agency (JST), Soft Nanomachines Project, CREST, Osaka University, Nanobiology Bld. 7F, 1 – 3 Yamadaoka, Suita, Osaka 565-0871, Japan

  2. 2

    Graduate School of Frontier, Biosciences, Osaka University, Nanobiology Bld. 7F, 1 – 3 Yamadaoka, Suita, Osaka 565-0871, Japan

Publication History

  1. Published Online: 23 MAY 2005
  2. Published Print: 26 JAN 2005

ISBN Information

Print ISBN: 9783527306909

Online ISBN: 9783527603763

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Keywords:

  • single biomolecule manipulation;
  • mechanical properties of biomolecules;
  • molecular motors;
  • measurements of the interaction forces

Summary

This chapter contains sections titled:

  • Single Molecule Manipulation

    • Glass Microneedle

    • Laser Trap

    • Space and Time Resolution of Nanometry

    • Molecular Glues

    • Comparisons of the Microneedle and Laser Trap Methods

  • Mechanical Properties of Biomolecules

    • Protein Polymers

    • Mechanically Induced Unfolding of Single Protein Molecules

    • Interacting Molecules

  • Manipulation and Molecular Motors

    • Manipulation of Actin Filaments

    • Manipulation of a Single Myosin Molecule

    • Unitary Steps of Myosin

    • Step Size and Unconventional Myosin

    • Manipulation of Kinesin

  • Different Types of Molecular Motors

  • Direct Measurements of the Interaction Forces

    • Electrostatic Force Between Positively Charged Surfaces

    • Surface Force Property of Myosin Filaments