Chapter 12. The C. elegans Centrosome during Early Embryonic Development

  1. Prof. Dr. Erich A. Nigg
  1. Laurence Pelletier,
  2. Thomas Müller-Reichert,
  3. Martin Srayko,
  4. Nurhan Özlü,
  5. Anne-Lore Schlaitz and
  6. Anthony A. Hyman

Published Online: 17 JUN 2005

DOI: 10.1002/3527603808.ch12

Centrosomes in Development and Disease

Centrosomes in Development and Disease

How to Cite

Pelletier, L., Müller-Reichert, T., Srayko, M., Özlü, N., Schlaitz, A.-L. and Hyman, A. A. (2004) The C. elegans Centrosome during Early Embryonic Development, in Centrosomes in Development and Disease (ed E. A. Nigg), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603808.ch12

Editor Information

  1. Max-Planck-Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, 82152 Martinsried, Germany

Author Information

  1. Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany

Publication History

  1. Published Online: 17 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527309801

Online ISBN: 9783527603800

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Keywords:

  • centrosomes in development;
  • centrosomes in disease;
  • Caenorhabditis elegans;
  • centrosome;
  • early embryonic development;
  • centrosome biogenesis;
  • cell division;
  • embryo;
  • centrioles;
  • pericentriolar material (PCM);
  • centrosome cycle;
  • centriole duplication;
  • PCM recruitment;
  • centrosome maturation;
  • centrosome functions;
  • spindle assembly;
  • microtubule nucleation;
  • anterior–posterior polarity;
  • spindle positioning

Summary

This chapter contains sections titled:

  • Introduction

    • C. elegans as a Tool to Study Centrosome Biogenesis

    • The First Cell Division of the C. elegans Embryo

  • The C. elegans Centrosome

    • The Centrioles

    • The Pericentriolar Material (PCM)

  • The Centrosome Cycle in C. elegans Embryos

    • Centriole Duplication

    • PCM Recruitment

    • Centrosome Maturation

  • Centrosome Functions

    • Spindle Assembly and Microtubule Nucleation

    • Determination of Anterior–Posterior Polarity

    • Spindle Positioning

  • Concluding Remarks

  • Acknowledgments

  • References