Chapter 17. Radiation Therapy and Centrosome Anomalies in Pancreatic Cancer

  1. Prof. Dr. Erich A. Nigg
  1. Norihiro Sato,
  2. Kazuhiro Mizumoto and
  3. Masao Tanaka

Published Online: 17 JUN 2005

DOI: 10.1002/3527603808.ch17

Centrosomes in Development and Disease

Centrosomes in Development and Disease

How to Cite

Sato, N., Mizumoto, K. and Tanaka, M. (2004) Radiation Therapy and Centrosome Anomalies in Pancreatic Cancer, in Centrosomes in Development and Disease (ed E. A. Nigg), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603808.ch17

Editor Information

  1. Max-Planck-Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, 82152 Martinsried, Germany

Author Information

  1. Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

Publication History

  1. Published Online: 17 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527309801

Online ISBN: 9783527603800

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Keywords:

  • centrosomes in development;
  • centrosomes in disease;
  • radiation therapy;
  • centrosome anomalies;
  • pancreatic cancer;
  • apoptosis;
  • mitotic cell death;
  • irradiation

Summary

This chapter contains sections titled:

  • Introduction

  • Radiation-induced Cell Death: Apoptosis or Mitotic Cell Death?

  • Centrosome Anomalies Induced by Radiation

  • The Mechanism(s) Leading to Centrosome Anomalies after Radiation Treatment

  • The Consequence of Centrosome Anomalies after Irradiation

  • Factors Affecting Centrosome Anomalies after Irradiation

  • Conclusions and Future Directions

  • References