Chapter 20. Basal Bodies and Microtubule Organization in Pathogenic Protozoa

  1. Prof. Dr. Erich A. Nigg
  1. Keith Gull,
  2. Laura Briggs and
  3. Sue Vaughan

Published Online: 17 JUN 2005

DOI: 10.1002/3527603808.ch20

Centrosomes in Development and Disease

Centrosomes in Development and Disease

How to Cite

Gull, K., Briggs, L. and Vaughan, S. (2004) Basal Bodies and Microtubule Organization in Pathogenic Protozoa, in Centrosomes in Development and Disease (ed E. A. Nigg), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603808.ch20

Editor Information

  1. Max-Planck-Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, 82152 Martinsried, Germany

Author Information

  1. Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK

Publication History

  1. Published Online: 17 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527309801

Online ISBN: 9783527603800

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Keywords:

  • centrosomes in development;
  • centrosomes in disease;
  • basal bodies;
  • microtubule organization;
  • pathogenic protozoa;
  • MTOC;
  • protozoal cells;
  • Trypanosoma brucei;
  • cell division;
  • Apicomplexa;
  • apical polar ring;
  • spindle MTOC;
  • cell morphogenesis;
  • cytoskeleton;
  • parasitism

Summary

This chapter contains sections titled:

  • Introduction and Appreciation

  • The “Dispersed” MTOC Complement of Protozoal Cells

  • The Trypanosoma brucei Microtubule Biology

    • The Spindle and Cell Division

    • Basal Bodies

  • The Microtubule Biology of the Apicomplexa

    • The Apical Polar Ring: A Unique Cytoplasmic MTOC

    • The Conoid

    • Apicomplexan Basal Bodies

    • The Spindle MTOC

    • Apicomplexan Cell Division and Cell Morphogenesis

  • Basal Bodies Are More than Just Microtubule Organizers: The Hitchhikers Guide to the Cytoskeleton!

  • Cytoskeletal Adaptations to Parasitism

  • Conclusion

  • Acknowledgments

  • References