Chapter 4. The Budding Yeast Spindle Pole Body: A Centrosome Analog

  1. Prof. Dr. Erich A. Nigg
  1. Suzanne van Kreeveld Naone and
  2. Mark Winey

Published Online: 17 JUN 2005

DOI: 10.1002/3527603808.ch4

Centrosomes in Development and Disease

Centrosomes in Development and Disease

How to Cite

van Kreeveld Naone, S. and Winey, M. (2004) The Budding Yeast Spindle Pole Body: A Centrosome Analog, in Centrosomes in Development and Disease (ed E. A. Nigg), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603808.ch4

Editor Information

  1. Max-Planck-Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, 82152 Martinsried, Germany

Author Information

  1. Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Porter Biosciences, 347 UCB, Boulder, CO 80309-0347, USA

Publication History

  1. Published Online: 17 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527309801

Online ISBN: 9783527603800

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Keywords:

  • centrosomes in development;
  • centrosomes in disease;
  • budding yeast;
  • spindle pole body;
  • halfbridge;
  • microtubule nucleation;
  • assembly of SPBs;
  • duplication of SPBs;
  • assembly of centrosomes;
  • duplication of centrosomes;
  • alteration of SPB function

Summary

This chapter contains sections titled:

  • Introduction

  • Molecular Composition of the Spindle Pole Body

    • The Central Plaque

    • The Inner Plaque

    • The Outer Plaque

    • Nuclear Membrane Factors

    • The Halfbridge

    • Structure Summary

  • Microtubule Nucleation

  • Assembly/Duplication of SPBs and Centrosomes

    • Electron Microscopic Description of Duplication

    • Cell Cycle Regulation of Duplication

    • Genetic Analysis of Duplication

  • Signaling Platform

  • Developmental Alteration of SPB Function

  • Parting Thoughts

  • Acknowledgments

  • References