Chapter 7. A Proteomic Approach to the Inventory of the Human Centrosome

  1. Prof. Dr. Erich A. Nigg
  1. Christopher J. Wilkinson2,
  2. Jens S. Andersen1,
  3. Matthias Mann1 and
  4. Erich A. Nigg2

Published Online: 17 JUN 2005

DOI: 10.1002/3527603808.ch7

Centrosomes in Development and Disease

Centrosomes in Development and Disease

How to Cite

Wilkinson, C. J., Andersen, J. S., Mann, M. and Nigg, E. A. (2004) A Proteomic Approach to the Inventory of the Human Centrosome, in Centrosomes in Development and Disease (ed E. A. Nigg), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603808.ch7

Editor Information

  1. Max-Planck-Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, 82152 Martinsried, Germany

Author Information

  1. 1

    Center for Experimental BioInformatics (CEBI), University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark

  2. 2

    Max-Planck-Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, 82152 Martinsried, Germany

Publication History

  1. Published Online: 17 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527309801

Online ISBN: 9783527603800

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Keywords:

  • centrosomes in development;
  • centrosomes in disease;
  • human centrosome;
  • centrosome component;
  • proteomic approach;
  • novel centrosome proteins;
  • cell cycle;
  • MS

Summary

This chapter contains sections titled:

  • Introduction

  • What is a Centrosome Component?

  • Composition of the Human Centrosome: A Proteomic Approach

  • Inspection of Novel Centrosome Proteins by Sequence Analysis

  • Cell Cycle Changes in Centrosome Composition

  • The Impact of MS on Centrosome Analysis during Cell Cycle and Development

  • Expanding Proteomic Information into Knowledge about Function

  • Conclusion and Prospects

  • Acknowledgments

  • References