Chapter 3. Role of Bacterial Porins in Antibiotic Susceptibility of Gram-Negative Bacteria

  1. Prof. Dr. Roland Benz
  1. Jean-Marie Pagès

Published Online: 21 JUN 2005

DOI: 10.1002/3527603875.ch3

Bacterial and Eukaryotic Porins: Structure, Function, Mechanism

Bacterial and Eukaryotic Porins: Structure, Function, Mechanism

How to Cite

Pagès, J.-M. (2004) Role of Bacterial Porins in Antibiotic Susceptibility of Gram-Negative Bacteria, in Bacterial and Eukaryotic Porins: Structure, Function, Mechanism (ed R. Benz), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603875.ch3

Editor Information

  1. Lehrstuhl für Biotechnologie, Biozentrum der Universität Würzburg, Am Hubland, 97074 Würzburg, Germany

Author Information

  1. Université de la Méditerranée, Faculté de Médecine, 27 Bd. Jean Moulin, 13385 Marseille cedex 05, France

Publication History

  1. Published Online: 21 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527307753

Online ISBN: 9783527603879

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Keywords:

  • bacterial porins;
  • antibiotic susceptibility of gram-negative bacteria;
  • antibiotic resistance;
  • in vitro mutagenesis analyses of porins

Summary

This chapter contains sections titled:

  • Introduction

  • Role of Porins in Antibiotic Resistance

    • Evolution of Clinical Isolates

    • Expression of a Modified Porin

  • In Vitro Mutagenesis Analyses of Porins and Modeling

    • Mutations in the Loop 3 Domain

    • Mutations in the Anti-loop 3 Domain

    • Modeling of β-Lactam in the OmpF Eyelet

  • Conclusion