Chapter 2. Transduction Channels in Hair Cells

  1. Prof. Dr. Stephan Frings2 and
  2. Dr. Jonathan Bradley3
  1. Robert Fettiplace

Published Online: 21 JUN 2005

DOI: 10.1002/3527603913.ch2

Transduction Channels in Sensory Cells

Transduction Channels in Sensory Cells

How to Cite

Fettiplace, R. (2004) Transduction Channels in Hair Cells, in Transduction Channels in Sensory Cells (eds S. Frings and J. Bradley), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527603913.ch2

Editor Information

  1. 2

    Department of Molecular Physiology, University of Heidelberg, Im Neuenheimer Feld 230, 69120 Heidelberg, Germany

  2. 3

    Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205, USA

Author Information

  1. Department of Physiology, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI 53706, USA

Publication History

  1. Published Online: 21 JUN 2005
  2. Published Print: 27 JUL 2004

ISBN Information

Print ISBN: 9783527308361

Online ISBN: 9783527603916



  • sensory cells;
  • transduction channels in hair cells;
  • gating mechanism;
  • channel kinetics;
  • gating compliance;
  • ionic selectivity;
  • MET channel adaption;
  • single-channel conductance


This chapter contains sections titled:

  • Introduction

  • Gating Mechanism: Channel Kinetics

    • Tip Links and Gating Springs

    • Gating Compliance

    • Three-state Channel Schemes

  • Ionic Selectivity

    • Blocking Compounds

  • MET Channel Adaptation

    • Ca2+ Regulation of Adaptation

    • The Function of Adaptation

  • Single-channel Conductance

    • Number of MET Channels Per Stereocilium

  • The MET Channel as a Member of the TRP Family

    • Properties of TRPV Channels

  • Conclusions