Chapter 14. Chemokine-Controlled Migration in Lymphoid Organogenesis and the Systemic Organization of Immunity

  1. Prof. Dr. Doris Wedlich
  1. Martin Lipp

Published Online: 9 AUG 2005

DOI: 10.1002/3527604669.ch14

Cell Migration in Development and Disease

Cell Migration in Development and Disease

How to Cite

Lipp, M. (2004) Chemokine-Controlled Migration in Lymphoid Organogenesis and the Systemic Organization of Immunity, in Cell Migration in Development and Disease (ed D. Wedlich), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527604669.ch14

Editor Information

  1. University of Karlsruhe, Institute of Zoology II, Kaiserstr. 12, 76131 Karlsruhe, Germany

Author Information

  1. Max-Delbrück-Center for Molecular Medicine (MDC), Robert Rössle Str. 10, 13125 Berlin, Germany

Publication History

  1. Published Online: 9 AUG 2005
  2. Published Print: 14 DEC 2004

ISBN Information

Print ISBN: 9783527305872

Online ISBN: 9783527604661

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Keywords:

  • cell migration;
  • chemokine-controlled migration;
  • lymphoid organogenesis;
  • systematic organization of immunity;
  • lymph node and splenic micro-architecture by homeostatic chemokines;
  • migration of lymphocytes and dendritic cells;
  • immune responses

Summary

This chapter contains sections titled:

  • Introduction

  • Lymphoid Organogenesis

    • The Chemokine Receptors CXCR5 and CCR7 in Lymph Node and Peyers Patch Development

    • A Positive Feedback Loop Drives the Initial Phase of Lymphoid Organ Development

  • Organization of Lymph Node and Splenic Micro-architecture by Homeostatic Chemokines

    • The Homeostatic Chemokine System in the Formation of the Splenic Micro-architecture

    • Lessons from CXCR5 and CCR7 Double Deficient Mice

  • Chemokine-controlled Migration of Lymphocytes and Dendritic Cells during Immune Responses

  • Concluding Remarks

  • Acknowledgments

  • References