Chapter 15. Keratinocyte Migration in Wound Healing

  1. Prof. Dr. Doris Wedlich
  1. Cord Brakebusch

Published Online: 9 AUG 2005

DOI: 10.1002/3527604669.ch15

Cell Migration in Development and Disease

Cell Migration in Development and Disease

How to Cite

Brakebusch, C. (2004) Keratinocyte Migration in Wound Healing, in Cell Migration in Development and Disease (ed D. Wedlich), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527604669.ch15

Editor Information

  1. University of Karlsruhe, Institute of Zoology II, Kaiserstr. 12, 76131 Karlsruhe, Germany

Author Information

  1. Max-Planck-Institut für Biochemie, Group “Regulation of Cytoskeletal Organization”, Am Klopferspitz 18a, 82152 Martinsried, Germany

Publication History

  1. Published Online: 9 AUG 2005
  2. Published Print: 14 DEC 2004

ISBN Information

Print ISBN: 9783527305872

Online ISBN: 9783527604661

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Keywords:

  • cell migration;
  • keratinocyte migration in wound healing;
  • skin;
  • wound healing;
  • keratinocyte activation;
  • growth factors;
  • cytokines;
  • transcription factors;
  • integrin factors;
  • extracellular matrix;
  • fibrin and plasmin

Summary

This chapter contains sections titled:

  • The Skin

  • Wound Healing

  • Models for Wound Healing

    • in vivo Models

    • in vitro Models

  • Initiation of Wound Healing and Keratinocyte Activation

  • Growth Factors and Cytokines

    • EGF Family of Growth Factors

    • FGF Family of Growth Factors

    • Extracellular Matrix Proteins

    • TGF, Chemokines and Cytokines

  • Transcription Factors

    • AP-1 Transcription Factor Family

    • E2F Transcription Factor Family

    • Activation of Stat3

    • NFkB

    • Peroxisome Proliferator Activated Receptors

    • Transcription Factor Smad3

  • Integrin Receptors

    • Keratinocyte Migration

    • Redistribution of Integrin Receptors

  • Extracellular Matrix

    • Fibrin and Plasmin

    • Fibronectin

    • Laminin

    • Matrix Metalloproteinases

  • Directed Migration of Keratinocytes

  • Migration Stopping and Deactivation

  • Conclusion

  • Acknowledgment

  • References