Chapter 13. Structure, Mechanism and Regulation of the Yeast and Coated Vesicle V-ATPases

  1. Masamitsu Futai2,
  2. Yoh Wada3 and
  3. Jack H. Kaplan4
  1. Elim Shao and
  2. Michael Forgac

Published Online: 6 DEC 2005

DOI: 10.1002/3527606122.ch13

Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology

Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology

How to Cite

Shao, E. and Forgac, M. (2005) Structure, Mechanism and Regulation of the Yeast and Coated Vesicle V-ATPases, in Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology (eds M. Futai, Y. Wada and J. H. Kaplan), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606122.ch13

Editor Information

  1. 2

    Division of Biological Sciences, Nanoscience and Nanotechnology Center, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan

  2. 3

    Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan

  3. 4

    University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, 900 S. Ashland Ave., Chicago, IL 60607, USA

Author Information

  1. Department of Physiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA

Publication History

  1. Published Online: 6 DEC 2005
  2. Published Print: 24 JUN 2004

ISBN Information

Print ISBN: 9783527306893

Online ISBN: 9783527606122

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Keywords:

  • ATPases;
  • V-type ATPases;
  • yeast and coated vesicle V-ATPases;
  • structure;
  • mechanism;
  • regulation;
  • function of V-ATPases;
  • relationship to F-ATPases;
  • nucleotide-binding subunits;
  • structure and function;
  • V0 subunits;
  • mechanism of ATP-dependent proton transport

Summary

This chapter contains sections titled:

  • Summary

  • Function of V-ATPases

  • Overall Structure of V-ATPases and Relationship to F-ATPases

  • Structure and Function of the Nucleotide-binding Subunits

  • Structure and Function of other V1 Subunits and Arrangement of Subunits in the V-ATPase Complex

  • Structure and Function of V0 Subunits

  • Mechanism of ATP-dependent Proton Transport

  • Regulation of V-ATPase Activity In Vivo

  • Conclusions

  • Acknowledgments

  • References