Chapter 18. Lytic Function of Vacuole, Molecular Dissection of Autophagy in Yeast
- Masamitsu Futai2,
- Yoh Wada3,
- Jack H. Kaplan4
Published Online: 6 DEC 2005
DOI: 10.1002/3527606122.ch18
Copyright © 2004 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology
Additional Information
How to Cite
Ohsumi, Y. (2005) Lytic Function of Vacuole, Molecular Dissection of Autophagy in Yeast, in Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology (eds M. Futai, Y. Wada and J. H. Kaplan), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606122.ch18
Editor Information
- 2
Division of Biological Sciences, Nanoscience and Nanotechnology Center, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
- 3
Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
- 4
University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, 900 S. Ashland Ave., Chicago, IL 60607, USA
Publication History
- Published Online: 6 DEC 2005
- Published Print: 24 JUN 2004
ISBN Information
Print ISBN: 9783527306893
Online ISBN: 9783527606122
- Summary
- Chapter
Keywords:
- ATPases;
- cell biology;
- pathophysiology of ATPases;
- compartments;
- lytic function of vacuole;
- molecular dissection of autophagy in yeast;
- genetic approaches to yeast autophagy;
- proteins involved in autophagy;
- function of the Apg proteins;
- disintegration of autophagic bodies;
- physiological roles of autophagy;
- autophagy in higher eukaryotes
Summary
This chapter contains sections titled:
Introduction
Vacuolar Protein Degradation in Yeast
Intracellular Bulk Degradation – Autophagy
Discovery of Autophagy in Yeast
Monitoring of Autophagy
Genetic Approaches to Yeast Autophagy
Characterization of Autophagy Defective Mutants
Proteins Involved in Autophagy
Apg12 Conjugation System
Apg8 Lipidation System
Apg1 Protein Kinase Complex
PI 3-kinase Complex
Function of the Apg Proteins
Disintegration of Autophagic Bodies in the Vacuole
Physiological Roles of Autophagy
Autophagy in Higher Eukaryotes
References