Chapter 4. The Na,K-ATPase: A Current Overview

  1. Masamitsu Futai1,
  2. Yoh Wada2 and
  3. Jack H. Kaplan3
  1. Jack H. Kaplan

Published Online: 6 DEC 2005

DOI: 10.1002/3527606122.ch4

Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology

Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology

How to Cite

Kaplan, J. H. (2004) The Na,K-ATPase: A Current Overview, in Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology (eds M. Futai, Y. Wada and J. H. Kaplan), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606122.ch4

Editor Information

  1. 1

    Division of Biological Sciences, Nanoscience and Nanotechnology Center, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan

  2. 2

    Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan

  3. 3

    University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, 900 S. Ashland Ave., Chicago, IL 60607, USA

Author Information

  1. University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, 900 S. Ashland Ave., Chicago, IL 60607, USA

Publication History

  1. Published Online: 6 DEC 2005
  2. Published Print: 24 JUN 2004

ISBN Information

Print ISBN: 9783527306893

Online ISBN: 9783527606122

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Keywords:

  • ATPases;
  • P-type ATPases;
  • Na,K-ATPase;
  • structure-function;
  • reaction mechanism;
  • roles of β-subunit;
  • third subunit;
  • regulation of Na,K-ATPase function;
  • importance of subunit isoforms

Summary

This chapter contains sections titled:

  • Introduction

  • Structure-Function and Reaction Mechanism

  • The Roles of the β-Subunit

  • A Third Subunit

  • Regulation of Na,K-ATPase Function

  • The Importance of Subunit Isoforms

  • Heterologous Expression of the Na,K-ATPase

  • Recent Highlights

  • Acknowledgments

  • References