Chapter 8. Plasma Membrane Calcium Pumps

  1. Masamitsu Futai2,
  2. Yoh Wada3 and
  3. Jack H. Kaplan4
  1. Ernesto Carafoli,
  2. Luisa Coletto and
  3. Marisa Brini

Published Online: 6 DEC 2005

DOI: 10.1002/3527606122.ch8

Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology

Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology

How to Cite

Carafoli, E., Coletto, L. and Brini, M. (2005) Plasma Membrane Calcium Pumps, in Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology (eds M. Futai, Y. Wada and J. H. Kaplan), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606122.ch8

Editor Information

  1. 2

    Division of Biological Sciences, Nanoscience and Nanotechnology Center, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan

  2. 3

    Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan

  3. 4

    University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, 900 S. Ashland Ave., Chicago, IL 60607, USA

Author Information

  1. Department of Biological Chemistry, University of Padova, Viale G. Colombo, 3, 35121 Padova, Italy

Publication History

  1. Published Online: 6 DEC 2005
  2. Published Print: 24 JUN 2004

ISBN Information

Print ISBN: 9783527306893

Online ISBN: 9783527606122

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Keywords:

  • ATPases;
  • P-type ATPases;
  • plasma membrane calcium pumps (PMCA);
  • isoforms of PMCA pump;
  • connection of PMCA pumps to apoptosis

Summary

This chapter contains sections titled:

  • Introduction

  • Pre-cloning Period

    • Early History

    • Regulation of the Pump

    • Isolated Pump

  • Cloning and Beyond

    • Isoforms of the PMCA Pump

    • Isoform Nomenclature

    • Tissue Distribution of the Isoforms

    • How do PMCA Pump Isoforms Differ Functionally?

    • Connection of PMCA Pumps to Apoptosis

    • Pathology

  • Final Remarks

  • References