Chapter 9. Proton Translocating ATPases: Introducing Unique Enzymes Coupling Catalysis and Proton Translocation through Mechanical Rotation
- Masamitsu Futai1,
- Yoh Wada2,
- Jack H. Kaplan3
Published Online: 6 DEC 2005
DOI: 10.1002/3527606122.ch9
Copyright © 2004 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology
Additional Information
How to Cite
Futai, M., Sun-Wada, G.-H. and Wada, Y. (2005) Proton Translocating ATPases: Introducing Unique Enzymes Coupling Catalysis and Proton Translocation through Mechanical Rotation, in Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology (eds M. Futai, Y. Wada and J. H. Kaplan), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606122.ch9
Editor Information
- 1
Division of Biological Sciences, Nanoscience and Nanotechnology Center, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
- 2
Division of Biological Sciences, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
- 3
University of Illinois at Chicago, Department of Biochemistry and Molecular Genetics, 900 S. Ashland Ave., Chicago, IL 60607, USA
Publication History
- Published Online: 6 DEC 2005
- Published Print: 24 JUN 2004
ISBN Information
Print ISBN: 9783527306893
Online ISBN: 9783527606122
- Summary
- Chapter
Keywords:
- ATPases;
- F-type ATPases;
- proton translocating ATPases;
- unique enzymes;
- coupling catalysis and proton translocation;
- mechanical rotation;
- catalytic mechanism of F-ATPase;
- roles of the γ subunit;
- rotational catalysis;
- F-ATPase holoenzyme;
- rotational catalysis of V-ATPase
Summary
This chapter contains sections titled:
Abbreviations
Introduction
Catalytic Mechanism of F-ATPase
Roles of the γ subunit: energy coupling by mechanical rotation
Roles of the γ Subunit in Energy Coupling
γ Subunit Rotation
Mutational Analysis of the γ Subunit Rotation
Rotational Catalysis of the F-ATPase Holoenzyme
Structure of Fo Sector and Proton Transport Pathway
Rotational Catalysis of the F-ATPase Holoenzyme
Rotational Catalysis of F-ATPase in Membranes
Rotational catalysis of V-ATPase
Catalytic Site and Proton Pathway
Subunit Rotation of V-ATPase During Catalysis
Epilogue
Acknowledgments
References