III. Contributions — E: Biomarkers

  1. Deutsche Forschungsgemeinschaft (DFG) and
  2. Senate Commission on Food Safety (SKLM)
  1. Prof. Dr. Helmut Bartsch1,
  2. J. Nair,
  3. Dr. LaVerne A. Mooney2 and
  4. Frederica P. Perera

Published Online: 5 JAN 2006

DOI: 10.1002/3527606246.ch3e

Carcinogenic and Anticarcinogenic Factors in Food: Symposium

Carcinogenic and Anticarcinogenic Factors in Food: Symposium

How to Cite

Bartsch, H., Nair, J., Mooney, L. A. and Perera, F. P. (2000) Contributions — E: Biomarkers, in Carcinogenic and Anticarcinogenic Factors in Food: Symposium (eds Deutsche Forschungsgemeinschaft (DFG) and Senate Commission on Food Safety (SKLM)), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606246.ch3e

Author Information

  1. 1

    Deutsches Krebsforschungszentrum, Division of Toxicology and Cancer Risk Factors, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany; Tel.: 00496221423300; FAX: 00496221423359

  2. 2

    Columbia University School of Public Health, Division of Environmental Health Sciences, 60 Haven Avenue B109, New York, NY 10032, USA; Tel.: 0012123047281; FAX: 001212544–1943

Publication History

  1. Published Online: 5 JAN 2006
  2. Published Print: 17 JUL 2000

ISBN Information

Print ISBN: 9783527271443

Online ISBN: 9783527606245

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Keywords:

  • carcinogenic factors;
  • anticarcinogenic factors;
  • foods;
  • biomarkers;
  • exocyclic DNA adducts;
  • oxidative stress;
  • dietary risk factors;
  • cancer;
  • chemopreventive approaches;
  • antioxidant vitamin trial in smokers

Summary

This chapter contains sections titled:

  • Exocyclic DNA Adducts as Biomarkers for Oxidative Stress, Dietary Risk Factors and Cancer Chemopreventive Approaches

    • Abstract

    • Introduction

    • Results and discussion

      • Increased exocyclic adduct formation as a consequence of LPO

    • Etheno adducts

    • Malondialdehyde-dG and propano-dG adducts

    • Perspectives

  • Biological Markers in Chemoprevention Research

    • Abstract

    • Introduction

    • Validation studies

      • Inter- and intra-individual variation

      • Transitional studies: Nutritional and genetic factors and DNA damage

      • PAH-DNA as a marker of lung cancer risk

      • Nutritional status and lung cancer risk

      • Genetic susceptibility to carcinogen exposure

    • Early vs intermediate markers

    • Modulation of biomarkers in an antioxidant vitamin trial in smokers

    • Conclusions