Chapter 1. Lipid Bilayers, Translocons and the Shaping of Polypeptide Structure

  1. Prof. Dr. Lukas K. Tamm
  1. Prof. Stephen H. White1,
  2. Tara Hessa2,
  3. Gunnar von Heijne2

Published Online: 29 MAR 2006

DOI: 10.1002/3527606769.ch1

Protein-Lipid Interactions: From Membrane Domains to Cellular Networks

Protein-Lipid Interactions: From Membrane Domains to Cellular Networks

How to Cite

White, S. H., Hessa, T. and von Heijne, G. (2006) Lipid Bilayers, Translocons and the Shaping of Polypeptide Structure, in Protein-Lipid Interactions: From Membrane Domains to Cellular Networks (ed L. K. Tamm), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606769.ch1

Editor Information

  1. Professor of Molecular Physiology and Biological Physics, University of Virginia, PO Box 800736, Charlottesville, VA 22908-0736, USA

Author Information

  1. 1

    Department of Physiology and Biophysics, Medical Sciences I-D346, University of California at Irvine, Irvine, CA 92697-4560, USA

  2. 2

    Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden

Publication History

  1. Published Online: 29 MAR 2006
  2. Published Print: 5 AUG 2005

ISBN Information

Print ISBN: 9783527311514

Online ISBN: 9783527606764

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Keywords:

  • lipid bilayers;
  • translocons;
  • shaping of polypeptide structure;
  • membrane proteins: intrinsic interactions and formative interactions

Summary

This chapter contains sections titled:

  • Introduction

  • Membrane Proteins: Intrinsic Interactions

    • Physical Determinants of Membrane Protein Stability: The Bilayer Milieu

    • Physical Determinants of Membrane Protein Stability: Energetics of Peptides in Bilayers

    • Physical Determinants of Membrane Protein Stability: Helix–Helix Interactions in Bilayers

  • Membrane Proteins: Formative Interactions

    • Connecting Translocon-assisted Folding to Physical Hydrophobicity Scales: The Interfacial Connection

    • Connecting Translocon-assisted Folding to Physical Hydrophobicity Scales: Transmembrane Insertion of Helices

  • Perspectives

  • References