Chapter 15. In vitro and Cellular Membrane-binding Mechanisms of Membrane-targeting Domains

  1. Prof. Dr. Lukas K. Tamm
  1. Prof. Wonhwa Cho,
  2. Dr. Robert V. Stahelin

Published Online: 29 MAR 2006

DOI: 10.1002/3527606769.ch15

Book Title

Protein-Lipid Interactions: From Membrane Domains to Cellular Networks

Protein-Lipid Interactions: From Membrane Domains to Cellular Networks

Additional Information

How to Cite

Cho, W. and Stahelin, R. V. (2006) In vitro and Cellular Membrane-binding Mechanisms of Membrane-targeting Domains, in Protein-Lipid Interactions: From Membrane Domains to Cellular Networks (ed L. K. Tamm), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606769.ch15

Editor Information

  1. Professor of Molecular Physiology and Biological Physics, University of Virginia, PO Box 800736, Charlottesville, VA 22908-0736, USA

Author Information

  1. Department of Chemistry (M/C 111), University of Illinois at Chicago, 845 W. Taylor Street, Chicago, IL 60607-7061, USA

Publication History

  1. Published Online: 29 MAR 2006
  2. Published Print: 5 AUG 2005

ISBN Information

Print ISBN: 9783527311514

Online ISBN: 9783527606764

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Keywords:

  • in vitro and cellular membrane-binding mechanisms of membrane-targeting domains;
  • membrane interactions of membrane-targeting domains;
  • lipid specificity;
  • C1 domains;
  • C2 domains;
  • PH domains;
  • FYVE domains;
  • PX domains;
  • ENTH and ANTH domains;
  • BAR domains;
  • FERM domains;
  • tubby domains

Summary

This chapter contains sections titled:

  • Introduction

  • Membrane Interactions of Membrane-targeting Domains

    • Interfacial Location of Membrane-targeting Domains

    • Energetics and Kinetics of Membrane–Protein Interactions

  • C1 Domains

    • Occurrence and Structure

    • Lipid Specificity

    • Membrane-binding Mechanisms

    • Subcellular Localization

  • C2 Domains

    • Occurrence and Structure

    • Lipid Specificity

    • Membrane Binding Mechanisms

    • Subcellular Localization

  • PH Domains

    • Occurrence, Structure and Lipid Specificity

    • Membrane-binding Mechanisms

    • Subcellular Localization

  • FYVE Domains

    • Occurrence, Structure and Lipid Specificity

    • Membrane-binding Mechanism

    • Subcellular Localization

  • PX Domains

    • Occurrence, Structure and Lipid Specificity

    • Membrane-binding Mechanism

    • Subcellular Localization

  • ENTH and ANTH Domains

    • Occurrence, Structure and Lipid Specificity

    • Membrane-binding Mechanism

  • BAR Domains

  • FERM Domains

  • Tubby Domains

  • Other Phosphoinositide-binding Domains

  • Perspectives

  • References

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