Chapter 7. Lipid Interactions of α-Helical Protein Toxins

  1. Prof. Dr. Lukas K. Tamm
  1. Dr. Gregor Anderluh1,
  2. Prof. Jeremy H. Lakey2

Published Online: 29 MAR 2006

DOI: 10.1002/3527606769.ch7

Book Title

Protein-Lipid Interactions: From Membrane Domains to Cellular Networks

Protein-Lipid Interactions: From Membrane Domains to Cellular Networks

Additional Information

How to Cite

Anderluh, G. and Lakey, J. H. (2006) Lipid Interactions of α-Helical Protein Toxins, in Protein-Lipid Interactions: From Membrane Domains to Cellular Networks (ed L. K. Tamm), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527606769.ch7

Editor Information

  1. Professor of Molecular Physiology and Biological Physics, University of Virginia, PO Box 800736, Charlottesville, VA 22908-0736, USA

Author Information

  1. 1

    Department of Biology, University of Ljubljana, Večna pot 111, 1000 Ljubljana, Slovenia

  2. 2

    Institute of Cell and Molecular Biosciences, University of Newcastle-upon-Tyne, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK

Publication History

  1. Published Online: 29 MAR 2006
  2. Published Print: 5 AUG 2005

ISBN Information

Print ISBN: 9783527311514

Online ISBN: 9783527606764

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CHAPTER TOOLS

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Keywords:

  • lipid interactions of α-helical protein toxins;
  • pore-forming colicins;
  • colicin–phospholipid complex;
  • actinoporins

Summary

This chapter contains sections titled:

  • Introduction

    • The Two Secondary Structures Compared

    • Lessons from a Potassium Channel

  • Pore-forming Colicins

    • Outer Membrane Interactions

    • Colicin A Requires Acidic Lipids

    • The Open Channel

    • The Colicin–Phospholipid Complex

    • Other Similar Proteins

  • Actinoporins

    • Initial Lipid Binding

    • Helix Insertion

    • The Oligomeric Pore

  • Conclusion

  • References

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