Chapter 10. Autoantibodies and Systemic Autoimmune Diseases

  1. Prof. Dr. K. Michael Pollard
  1. Karsten Conrad,
  2. Michael Bachmann

Published Online: 31 MAY 2006

DOI: 10.1002/3527607854.ch10

Book Title

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Additional Information

How to Cite

Conrad, K. and Bachmann, M. (2006) Autoantibodies and Systemic Autoimmune Diseases, in Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease (ed K. M. Pollard), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527607854.ch10

Editor Information

  1. Department of Molecular and Experimental Medicine, The Scripps Research Institute, MEM 131, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA

Author Information

  1. Institute of Immunology, Medical Faculty of the Technical University Dresden, Fetscherstrasse 74, 01307 Dresden, Germany

Publication History

  1. Published Online: 31 MAY 2006
  2. Published Print: 25 NOV 2005

ISBN Information

Print ISBN: 9783527311415

Online ISBN: 9783527607853

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CHAPTER TOOLS

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Keywords:

  • autoantibodies;
  • autoimmunity;
  • autoantibodies and systemic autoimmune diseases;
  • characteristics and classification of systemic autoimmune diseases;
  • distinguishing features of systemic autoimmune disease-specific antibodies

Summary

This chapter contains sections titled:

  • Characteristics and Classification of Systemic Autoimmune Diseases

  • Distinguishing Features of Systemic Autoimmune Disease-Specific Autoantibodies

    • Heterogeneity of the Autoimmune Response

    • Racial/Ethnic Variations in Frequency, Epitope Recognition, and Clinical Relevance of Disease-related Autoantibodies

    • Autoantibodies as Predictors (Early Markers) of Disease

    • Problems of Standardization of AAB Testing

  • Autoantibodies as Diagnostic and/or Prognostic Markers in Systemic Autoimmune Diseases

    • Autoantibodies in Rheumatoid Arthritis

    • Autoantibodies in Systemic Lupus Erythematosus

    • Autoantibodies in Sjögren's Syndrome

    • Autoantibodies in Systemic Sclerosis (Scleroderma)

      • Characteristics, Heterogeneity, and Subsets of Systemic Sclerosis

      • Anti-centromere Antibodies

      • Anti-topoisomerase I Antibodies

      • Anti-nucleolar and Anti-RNA Polymerase Antibodies

    • Autoantibodies in Idiopathic Inflammatory Myopathies

    • Autoantibodies in Mixed Connective Tissue Disease

    • Autoantibodies in Polymyositis-Scleroderma Overlap Syndrome (Scleromyositis)

    • The Antiphospholipid Syndrome

    • ANCA-associated Vasculitides

      • Anti-proteinase 3 Antibodies (PR3-ANCAs)

      • Anti-myeloperoxidase Antibodies (MPO-ANCAs)

  • Summary and Perspectives

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