Chapter 13. Autoantibodies and Organ-specific Autoimmunity

  1. Prof. Dr. K. Michael Pollard
  1. H. Bantel,
  2. J. Kneser,
  3. M.P. Manns

Published Online: 31 MAY 2006

DOI: 10.1002/3527607854.ch13

Book Title

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Additional Information

How to Cite

Bantel, H., Kneser, J. and Manns, M.P. (2006) Autoantibodies and Organ-specific Autoimmunity, in Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease (ed K. M. Pollard), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527607854.ch13

Editor Information

  1. Department of Molecular and Experimental Medicine, The Scripps Research Institute, MEM 131, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA

Author Information

  1. Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30623 Hannover, Germany

Publication History

  1. Published Online: 31 MAY 2006
  2. Published Print: 25 NOV 2005

ISBN Information

Print ISBN: 9783527311415

Online ISBN: 9783527607853

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CHAPTER TOOLS

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Keywords:

  • autoimmunity;
  • autoantibodies and organ-specific autoimmunity;
  • role of autoantibodies in tissue-specific organ damage;
  • autoantibodies and autoantigens in autoimmune hepatitis;
  • primary biliary cirrhosis

Summary

This chapter contains sections titled:

  • Role of Autoantibodies in Tissue-specific Organ Damage

  • Autoantibodies and Autoantigens in Autoimmune Hepatitis

  • Autoantibodies Frequently Associated with Autoimmune Hepatitis Type 1

    • Antinuclear Antibodies

    • Anti–Smooth Muscle Antibodies

    • Perinuclear Anti-neutrophil Cytoplasmic Antibodies (pANCAs) and Antibodies to Asialoglycoprotein Receptor (anti-ASGPRs)

  • Autoantibodies and Autoantigens Associated with Autoimmune Hepatitis Type

    • Liver Kidney Microsomal Antibodies

    • Anti-cytosol Autoantibodies Type 1 (anti-LC-1)

  • Autoantibodies and Autoantigens Associated with Autoimmune Hepatitis Type 3

  • Autoantibodies Associated with Primary Biliary Cirrhosis

  • Autoantibodies in Overlap Syndrome Between Autoimmune Hepatitis and Primary Biliary Cirrhosis

  • Discussion and Conclusions

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