Chapter 14. Autoantibodies in Autoimmune Thyroid Disease

  1. Prof. Dr. K. Michael Pollard
  1. Osvaldo Martinez1,
  2. Bellur S. Prabhakar2

Published Online: 31 MAY 2006

DOI: 10.1002/3527607854.ch14

Book Title

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Additional Information

How to Cite

Martinez, O. and Prabhakar, B. S. (2006) Autoantibodies in Autoimmune Thyroid Disease, in Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease (ed K. M. Pollard), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527607854.ch14

Editor Information

  1. Department of Molecular and Experimental Medicine, The Scripps Research Institute, MEM 131, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA

Author Information

  1. 1

    Department of Microbiology, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA

  2. 2

    Department of Microbiology and Immunology, University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, USA

Publication History

  1. Published Online: 31 MAY 2006
  2. Published Print: 25 NOV 2005

ISBN Information

Print ISBN: 9783527311415

Online ISBN: 9783527607853

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CHAPTER TOOLS

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Keywords:

  • autoimmunity;
  • autoantibodies in autoimmune thyroid disease;
  • thyroid gland;
  • autoimmune diseases of the thyroid;
  • autoantibodies in thyroiditis;
  • role of genetic factors

Summary

This chapter contains sections titled:

  • The Thyroid Gland

  • Autoimmune Diseases of the Thyroid

  • Autoantibodies in Thyroiditis

  • TSHR-mediated Autoimmunity

  • Development of Autoantibodies Against TSHR

  • The Role of Genetic Factors

  • The Role of Environmental Factors

  • Assays for TSHR Autoantibodies

  • Thyrotropin Receptor Down-modulation

  • Functional Domains of TSHR

  • TSAb Epitopes in GD

  • TSBAbs with TBII Activity

  • The Heterogeneous and Homogeneous TSAbs

  • Immunomodulation

  • Conclusions

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